Can CBD Help with Period Cramps? Exploring the Science Behind the Relief

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Cannabidiol (CBD), a non-intoxicating compound derived from the hemp plant, has long been recognized for its pain-modulating, anti-inflammatory, and relaxing properties. For many people dealing with chronic pain, anxiety, or sleeplessness, CBD has proven to be a valuable tool since its legalization. But what many people don’t realize yet is that CBD may also offer relief for menstrual cramps, a domain of women’s health that remains significantly under-researched, even as 84% of women report experiencing moderate to severe menstrual pain, according to a 2023 survey by Statista.
How Does CBD Help Reduce Menstrual Pain?
CBD interacts with the body’s endocannabinoid system (ECS), a network found in the body of all vertebrates involved in maintaining balance across multiple physiological processes, including pain perception, inflammation, and muscle contractions. The ECS is made of receptors scattered throughout the brain, immune system, and peripheral tissues. While CBD doesn’t bind strongly to these receptors, it influences them indirectly by modulating the activity of neurotransmitters and inflammatory responses. This modulation can reduce pain intensity and muscle relaxation, including in the uterus, where period cramps originate.
Cramping pain, also known as dysmenorrhea, is often caused by the release of prostaglandins, hormone-like substances that trigger uterine muscles to contract. Higher levels of prostaglandins are associated with more intense cramps. CBD appears to influence the production of prostaglandin, thus reducing menstrual cramping pain.
What Studies Say About CBD and Period Cramps
Although formal clinical research on CBD for menstrual pain is still emerging (it is one of many under-studied fields relating to women’s health), preliminary studies offer hopeful insights. A 2024 study published in Experimental and Clinical Psychopharmacology showed that women who took CBD isolate orally during their cycles reported a reduction in menstrual-related symptoms, including cramping, stress, anxiety and mood disturbance. Another observational study published in npj Women’s Health in 2024 using high-CBD vaginal suppositories showed significant improvements in pain severity and menstrual-related symptoms.
Personal Experiences Using CBD
While we wait for more research in this area to emerge, it is worth noting that many people are already experiencing meaningful relief through the use of CBD. The following testimonials volunteered by women who have used Dr Vaz’s CBD Jammin Jellies reflect how cannabidiol is making a difference:
“I discovered a few years ago that CBD was pretty good at calming cramps whenever I have my period. It reduces the pain by 80% or more. I always prefer natural alternatives whenever available, so I always keep a jar of CBD Jammin Jellies at my house for that time of the month.” — Tina M.R., Leesville, TX
“The CBD jellies helped my cramps so much! Midol wasn’t working and I legit was struggling that day… I really struggle with cramps post having kids and it really helped me!” — Rachael C., from Seguin, TX
Which Products Work Best to Soothe Menstrual Cramps?
CBD isolate edibles and tinctures are the most popular options to ward off menstrual cramps, with effects typically lasting 3 to 6 hours, depending on the dose and the individual. These delivery methods allow for systemic absorption, making them effective for addressing cramping throughout the pelvic region.
As with all therapeutic options, individual responses vary. Patients and consumers are encouraged to consult a knowledgeable medical professional before adding CBD (or other cannabinoids) to their wellness routine. But given the growing number of success stories and promising early data, CBD may well become a widely embraced natural option for period relief in the future. Now, let us spread the word!
FDA Disclosure: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.